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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMNAT1
All Species:
1.52
Human Site:
S135
Identified Species:
2.56
UniProt:
Q9HAN9
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAN9
NP_073624.2
279
31932
S135
K
W
T
E
T
Q
D
S
S
Q
K
K
S
L
E
Chimpanzee
Pan troglodytes
XP_001168527
254
29013
K114
T
Q
D
S
S
Q
K
K
S
L
E
P
K
T
K
Rhesus Macaque
Macaca mulatta
XP_001118727
179
20456
K39
K
Q
D
S
S
Q
K
K
S
L
E
P
K
T
K
Dog
Lupus familis
XP_536739
279
31883
F135
W
A
E
Q
R
Q
D
F
S
Q
K
K
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPA7
285
32337
D135
K
W
A
D
Q
K
Q
D
S
S
P
Q
K
P
Q
Rat
Rattus norvegicus
Q0HA29
307
34426
Q135
Q
P
Q
H
E
N
T
Q
P
I
Y
Q
N
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507826
272
31049
C132
A
L
E
L
K
L
L
C
G
A
D
L
L
E
S
Chicken
Gallus gallus
XP_417605
284
32371
H138
R
K
Q
E
P
N
R
H
D
P
I
K
K
K
N
Frog
Xenopus laevis
NP_001091188
278
32072
K136
R
E
N
S
H
Q
D
K
P
N
S
Y
L
Q
E
Zebra Danio
Brachydanio rerio
Q6PC93
304
34191
A135
Q
P
Q
N
E
T
S
A
I
Y
Q
N
T
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651315
389
43777
N148
N
Y
I
N
N
H
I
N
S
G
G
G
G
G
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91851
223
25149
T83
R
A
D
D
W
E
C
T
R
T
T
W
T
R
T
Sea Urchin
Strong. purpuratus
XP_783084
287
32645
P146
N
L
R
K
N
E
P
P
A
S
N
D
T
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53204
395
44891
H146
E
D
Y
E
F
P
V
H
R
L
T
K
K
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
62
86.3
N.A.
80.6
28.6
N.A.
63.7
69.7
60.9
26.9
N.A.
33.9
N.A.
26.1
47.3
Protein Similarity:
100
89.6
62.3
92.1
N.A.
89.4
48.5
N.A.
76.3
82
76.3
46.7
N.A.
48
N.A.
44
67.9
P-Site Identity:
100
13.3
20
60
N.A.
20
0
N.A.
0
13.3
20
0
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
33.3
40
66.6
N.A.
46.6
20
N.A.
0
20
26.6
33.3
N.A.
26.6
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
0
0
0
8
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
22
15
0
0
22
8
8
0
8
8
0
0
8
% D
% Glu:
8
8
15
22
15
15
0
0
0
0
15
0
0
15
22
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
8
8
8
8
0
% G
% His:
0
0
0
8
8
8
0
15
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
8
8
8
0
0
0
0
% I
% Lys:
22
8
0
8
8
8
15
22
0
0
15
29
36
8
15
% K
% Leu:
0
15
0
8
0
8
8
0
0
22
0
8
15
22
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
15
15
15
0
8
0
8
8
8
8
0
22
% N
% Pro:
0
15
0
0
8
8
8
8
15
8
8
15
0
8
0
% P
% Gln:
15
15
22
8
8
36
8
8
0
15
8
15
0
8
15
% Q
% Arg:
22
0
8
0
8
0
8
0
15
0
0
0
0
8
0
% R
% Ser:
0
0
0
22
15
0
8
8
43
15
8
0
15
8
8
% S
% Thr:
8
0
8
0
8
8
8
8
0
8
15
0
22
15
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% V
% Trp:
8
15
0
0
8
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _